Description

4,5-Dichloro-8-Methylquinoline is a halogenated quinoline derivative that serves as a versatile and high-value synthetic intermediate in advanced chemical manufacturing. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific quinoline-based frameworks into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or acting as kinase inhibitors.
• Agrochemical Synthesis: Building block for developing advanced fungicides, herbicides, and plant growth regulators with enhanced activity.
• Material Science Research: Used in the creation of organic semiconductors, ligands for metal-organic frameworks (MOFs), and photoactive compounds.
• Chemical Research & Development: Serves as a standard or starting material for methodological studies in organic synthesis and catalysis.
• Dye & Pigment Industry: Intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Coordination Chemistry: Acts as a chelating ligand for various transition metals in catalyst design.

Basic Information

Product Name	4,5-Dichloro-8-Methylquinoline
CAS No.	948292-29-3
Molecular Formula	C₁₀H₇Cl₂N
Molecular Weight	212.08 g/mol
Synonyms	8-Methyl-4,5-dichloroquinoline; 4,5-Dichloro-8-methylquinoline; Quinoline, 4,5-dichloro-8-methyl-; 948292-29-3
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-8-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.