Description

2-Chloro-7-Fluoroquinoline-3-Carbonitrile is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel quinolone-based antibiotics, kinase inhibitors, and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a precursor for organic semiconductors, liquid crystals, and fluorescent dyes due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry and proteomics research.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies in heterocyclic chemistry and cross-coupling reactions.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	2-Chloro-7-Fluoroquinoline-3-Carbonitrile
CAS No.	948291-81-4
Molecular Formula	C10H4ClFN2
Molecular Weight	206.60 g/mol
Synonyms	2-Chloro-7-fluoroquinoline-3-carbonitrile; 3-Cyano-2-chloro-7-fluoroquinoline; 7-Fluoro-2-chloroquinoline-3-carbonitrile; 948291-81-4; Quinoline-3-carbonitrile, 2-chloro-7-fluoro-; 2-Chloro-7-fluoro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-7-Fluoroquinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.