Description

2,7-Dichloro-8-Methylquinoline-3-Carbonitrile is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and nitrile-substituted structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting infectious diseases or cancer, due to the quinoline core's biological relevance.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the chlorinated quinoline structure can contribute to bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, or metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyano group transformations.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized quinoline-based dyes and colorants.
• Ligand Synthesis: Useful for preparing novel nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2,7-Dichloro-8-Methylquinoline-3-Carbonitrile
CAS No.	948291-65-4
Molecular Formula	C11H6Cl2N2
Molecular Weight	237.09 g/mol
Synonyms	8-Methyl-2,7-dichloroquinoline-3-carbonitrile; 3-Cyano-2,7-dichloro-8-methylquinoline; 2,7-Dichloro-8-methyl-3-quinolinecarbonitrile; Quinoline-3-carbonitrile, 2,7-dichloro-8-methyl-; 948291-65-4; 2,7-Dichloro-8-methylquinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2,7-Dichloro-8-Methylquinoline-3-Carbonitrile is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.