Description

2-Chloro-3-Chloromethyl-7-Fluoroquinoline is a high-purity, multi-functional halogenated quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its versatile molecular scaffold, which allows for the efficient synthesis of complex molecules with tailored biological and material properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs) targeting bacterial infections.
• Agrochemical Synthesis: Used in the development of next-generation fungicides and herbicides, leveraging the quinoline core for enhanced bioactivity and environmental stability.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-deficient aromatic system.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized, light-fast quinoline-based dyes and colorants.
• Ligand Synthesis for Catalysis: Utilized to synthesize complex nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other organic transformations.

Basic Information

Product Name	2-Chloro-3-Chloromethyl-7-Fluoroquinoline
CAS No.	948291-38-1
Molecular Formula	C11H6Cl2FN
Molecular Weight	246.08 g/mol
Synonyms	7-Fluoro-2-chloro-3-(chloromethyl)quinoline; 3-(Chloromethyl)-2-chloro-7-fluoroquinoline; 2-Chloro-3-chloromethyl-7-fluoroquinoline; 948291-38-1; Quinoline, 2-chloro-3-(chloromethyl)-7-fluoro-; 7-fluoro-2-chloro-3-chloromethylquinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Chloromethyl-7-Fluoroquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and all relevant physical and chemical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.