Description

8-Bromo-2-Chloro-7-Methoxyquinoline-3-Carbonitrile is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and nitrile-substituted structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its halogenated quinoline core.
• Material Science Research: Serves as a monomer or functional unit in the development of organic electronic materials and photoactive compounds.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, multi-substituted quinoline frameworks.

Basic Information

Product Name	8-Bromo-2-Chloro-7-Methoxyquinoline-3-Carbonitrile
CAS No.	948291-24-5
Molecular Formula	C11H6BrClN2O
Molecular Weight	297.53 g/mol
Synonyms	8-Bromo-2-chloro-7-methoxyquinoline-3-carbonitrile; 3-Cyano-8-bromo-2-chloro-7-methoxyquinoline; Quinoline-3-carbonitrile, 8-bromo-2-chloro-7-methoxy-; 948291-24-5; 8-Br-2-Cl-7-MeO-quinoline-3-CN
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Chloro-7-Methoxyquinoline-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.