Description

2-Chloro-3-Chloromethyl-6-Fluoroquinoline is a high-value fluorinated quinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated structure makes it an essential building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components, due to the quinoline scaffold's electron-transport properties.
• Chemical Biology Probes: Serves as a versatile scaffold for creating fluorescent tags and molecular probes used in diagnostic assays and cellular imaging.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and nucleophilic substitutions to introduce the functionalized quinoline moiety into more complex molecular architectures.

Basic Information

Product Name	2-Chloro-3-Chloromethyl-6-Fluoroquinoline
CAS No.	948291-04-1
Molecular Formula	C11H6Cl2FN
Molecular Weight	230.08 g/mol
Synonyms	6-Fluoro-2-chloro-3-(chloromethyl)quinoline; 3-(Chloromethyl)-2-chloro-6-fluoroquinoline; 2-Chloro-6-fluoro-3-quinolinylmethyl chloride; 948291-04-1; Quinoline, 2-chloro-3-(chloromethyl)-6-fluoro-; 2-Chloro-3-chloromethyl-6-fluoroquinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Chloromethyl-6-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.