Description

2-Chloro-3-Chloromethyl-5,8-Dimethylquinoline is a versatile and high-value halogenated quinoline derivative that serves as a critical synthetic intermediate. Its molecular structure makes it an essential building block for the development of advanced functional materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or acting as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new fungicides, herbicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic semiconductors, liquid crystals, or advanced polymers.
• Coordination Chemistry: Acts as a ligand precursor for creating metal-organic frameworks (MOFs) or catalysts due to its potential chelating sites.
• Dye and Pigment Industry: Intermediate for synthesizing specialized quinoline-based dyes and fluorescent markers.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing complex molecular architectures.

Basic Information

Product Name	2-Chloro-3-Chloromethyl-5,8-Dimethylquinoline
CAS No.	948290-65-1
Molecular Formula	C12H11Cl2N
Molecular Weight	240.13 g/mol
Synonyms	2-Chloro-3-(chloromethyl)-5,8-dimethylquinoline; 5,8-Dimethyl-2-chloro-3-chloromethylquinoline; Quinoline, 2-chloro-3-(chloromethyl)-5,8-dimethyl-; 3-(Chloromethyl)-2-chloro-5,8-dimethylquinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Chloromethyl-5,8-Dimethylquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.