Description

2-Chloro-3,6,8-Trimethylquinoline is a high-purity, synthetically valuable quinoline derivative. This compound serves as a crucial advanced intermediate in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily sought after by research and development teams, as well as production units, in the pharmaceutical, agrochemical, and advanced material science sectors for its role in constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to the bioactivity of the quinoline core.
• Material Science Research: Acts as a precursor for the development of organic semiconductors, light-emitting diodes (OLEDs), and photoactive materials.
• Dye and Pigment Industry: Serves as an intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Catalyst Ligand Synthesis: Utilized in the preparation of complex ligands for catalytic systems in asymmetric synthesis.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and contract research organizations (CROs).

Basic Information

Product Name	2-Chloro-3,6,8-Trimethylquinoline
CAS No.	948290-53-7
Molecular Formula	C₁₂H₁₂ClN
Molecular Weight	205.68 g/mol
Synonyms	2-Chloro-3,6,8-trimethylquinoline; Quinoline, 2-chloro-3,6,8-trimethyl-; 3,6,8-Trimethyl-2-chloroquinoline; 2-Chloro-3,6,8-trimethyl-quinoline; 948290-53-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,6,8-Trimethylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.