Description

7-Chloro-8-Methylquinoline-2,3-Dicarboxylic Acid Diethyl Ester is a high-purity, functionalized quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Employed in the synthesis of conjugated molecules for applications in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile building block for academic and industrial R&D focused on heterocyclic and medicinal chemistry.
• Dye and Pigment Intermediate: Used in the production of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	7-Chloro-8-Methylquinoline-2,3-Dicarboxylic Acid Diethyl Ester
CAS No.	948290-46-8
Molecular Formula	C₁₇H₁₈ClNO₄
Molecular Weight	335.78 g/mol
Synonyms	Diethyl 7-Chloro-8-methylquinoline-2,3-dicarboxylate; 7-Chloro-8-methylquinoline-2,3-dicarboxylic acid diethyl ester; 2,3-Quinolinedicarboxylic acid, 7-chloro-8-methyl-, diethyl ester; Ethyl 7-chloro-8-methyl-2,3-quinolinedicarboxylate; 7-Chloro-8-methyl-2,3-quinolinedicarboxylic acid diethyl ester
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Methylquinoline-2,3-Dicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.