Description

(1R,3R)-3-Aminocyclopentan-1-ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its defined stereochemistry, which is critical for imparting specific biological activity in final active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries engaged in the development of novel therapeutics, particularly in areas requiring rigid, functionalized cyclopentane scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex molecules with high enantiomeric purity in medicinal chemistry.
• Peptidomimetics & Bioisosteres: Used to introduce constrained, amino-alcohol motifs that mimic peptide structures for improved metabolic stability.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Agrochemical Research: Employed in the synthesis of advanced, chiral active ingredients for crop protection.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and pharmacology within research institutions.

Basic Information

Product Name	(1R,3R)-3-Aminocyclopentan-1-ol Hydrochloride
CAS No.	946826-74-0
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(1R,3R)-3-Aminocyclopentanol Hydrochloride; (1R,3R)-3-Amino-1-cyclopentanol HCl; (1R,3R)-1-Amino-3-hydroxycyclopentane Hydrochloride; trans-3-Aminocyclopentanol Hydrochloride; (1R,3R)-Aminocyclopentanol HCl; 3-Amino-1-cyclopentanol, (1R,3R)-, hydrochloride; 946826-74-0
EINECS	Contact for details

Quality Control

Our (1R,3R)-3-Aminocyclopentan-1-ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.