Description

2-(Chloromethyl)-4-Oxo-1,4-Dihydro-6-Quinolinecarboxamide (Saltdata: Free) is a specialized quinoline derivative that serves as a crucial advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting complex therapeutic areas. It is primarily needed by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinoline-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries of compounds for biological screening.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic pathways and heterocyclic chemistry.

Basic Information

Product Name	2-(Chloromethyl)-4-Oxo-1,4-Dihydro-6-Quinolinecarboxamide (Saltdata: Free)
CAS No.	946755-57-3
Molecular Formula	C12H9ClN2O2
Molecular Weight	248.66 g/mol
Synonyms	2-(Chloromethyl)-4-oxo-1,4-dihydroquinoline-6-carboxamide; 6-Quinolinecarboxamide, 2-(chloromethyl)-1,4-dihydro-4-oxo-; 2-(Chloromethyl)-1,4-dihydro-4-oxo-6-quinolinecarboxamide; 2-(Chloromethyl)-4-oxo-1H-quinoline-6-carboxamide; 946755-57-3 (CAS); Free base of 2-(Chloromethyl)-4-oxo-1,4-dihydro-6-quinolinecarboxamide
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-4-Oxo-1,4-Dihydro-6-Quinolinecarboxamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.