Description

2-Bromo-4-(Pyrrolidin-1-Yl)Benzaldehyde is a versatile and high-value aromatic aldehyde building block featuring a bromine substituent and a pyrrolidine moiety. This compound matters for its dual functionality, offering reactive sites for cross-coupling reactions and further derivatization, making it a critical intermediate in advanced synthetic chemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs and photovoltaics.
• Chemical Synthesis: The aldehyde group is ideal for condensation reactions (e.g., forming Schiff bases), while the bromine atom enables Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-Bromo-4-(Pyrrolidin-1-Yl)Benzaldehyde
CAS No.	946705-58-4
Molecular Formula	C11H12BrNO
Molecular Weight	254.13 g/mol
Synonyms	4-(Pyrrolidin-1-yl)-2-bromobenzaldehyde; 2-Bromo-4-(1-pyrrolidinyl)benzaldehyde; 2-Bromo-4-pyrrolidin-1-ylbenzaldehyde; Benzaldehyde, 2-bromo-4-(1-pyrrolidinyl)-; 946705-58-4; 2-Bromo-4-pyrrolidinobenzaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is light-sensitive and easily oxidized; allow the sealed container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.