Description

8-Chloro-2-(Chloromethyl)-4(1H)-Quinolinone is a high-purity, free-form quinolinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block, enabling the construction of complex molecular architectures with potential biological activity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for use in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates with potential therapeutic applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis: Versatile substrate for various organic transformations, including nucleophilic substitutions and cyclization reactions.
• Material Science Research: Potential precursor for the development of organic electronic materials or fluorescent dyes.

Basic Information

Product Name	8-Chloro-2-(Chloromethyl)-4(1H)-Quinolinone (Saltdata: Free)
CAS No.	946692-43-9
Molecular Formula	C10H7Cl2NO
Molecular Weight	228.08 g/mol
Synonyms	8-Chloro-2-(chloromethyl)-1,4-dihydroquinolin-4-one; 8-Chloro-2-(chloromethyl)-4-hydroxyquinoline; 4(1H)-Quinolinone, 8-chloro-2-(chloromethyl)-; 946692-43-9; 8-Chloro-2-chloromethylquinolin-4(1H)-one; 2-(Chloromethyl)-8-chloro-4(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(Chloromethyl)-4(1H)-Quinolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.