Description

tert-Butyl 4-Cyano-2,2-Dimethyl-3-Oxopyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidinone scaffold. This compound is a critical building block in modern organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Protease Inhibitor Research: Serves as a core structural component in the development of protease inhibitors due to its pyrrolidinone moiety.
• Peptidomimetic Chemistry: Used to create peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Agrochemical Synthesis: Employed in the research and development of advanced agrochemicals and plant protection agents.
• Material Science Research: Acts as a precursor for specialty polymers and functional materials requiring specific heterocyclic structures.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in academic and contract research organizations (CROs).

Basic Information

Product Name	tert-Butyl 4-Cyano-2,2-Dimethyl-3-Oxopyrrolidine-1-Carboxylate
CAS No.	946497-94-5
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	1-Boc-4-cyano-2,2-dimethyl-3-oxopyrrolidine; 1-(tert-Butoxycarbonyl)-4-cyano-2,2-dimethyl-3-pyrrolidinone; 3-Oxo-2,2-dimethyl-4-cyanopyrrolidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-cyano-2,2-dimethyl-3-oxo-1-pyrrolidinecarboxylate; 4-Cyano-2,2-dimethyl-3-oxo-1-pyrrolidinecarboxylic acid tert-butyl ester; Boc-4-CN-2,2-dimethyl-3-oxopyrrolidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-Cyano-2,2-Dimethyl-3-Oxopyrrolidine-1-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.