Description

4-n-Acetylamino-1-Oxaspiro[5.5]Undecane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel spirocyclic drug candidates targeting neurological and metabolic pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization stages for structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis under GMP conditions.
• Academic & Contract Research: Employed in university and CRO laboratories for exploring new chemical spaces and bioactive molecule libraries.
• Fine Chemical Synthesis: Intermediate for creating specialized ligands, catalysts, or other complex organic molecules with spiro architectures.

Basic Information

Product Name	4-n-Acetylamino-1-Oxaspiro[5.5]Undecane
CAS No.	946051-14-5
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	4-Acetylamino-1-oxaspiro[5.5]undecane; 1-Oxaspiro[5.5]undecan-4-amine, N-acetyl-; 4-(Acetylamino)-1-oxaspiro[5.5]undecane; N-(1-Oxaspiro[5.5]undecan-4-yl)acetamide; 4-Acetamido-1-oxaspiro[5.5]undecane; Spirocyclic Acetamide Intermediate; CAS 946051-14-5
EINECS	Contact for details

Quality Control

Our 4-n-Acetylamino-1-Oxaspiro[5.5]Undecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.