Description

2,3-Dihydro-2-[4-(Trifluoromethyl)Phenyl]-4(1H)-Quinolinone is a specialized heterocyclic organic compound featuring a quinolinone core substituted with a trifluoromethylphenyl group. This structure makes it a valuable key intermediate in the synthesis of advanced pharmaceutical and agrochemical agents, where the trifluoromethyl moiety is prized for its ability to modulate biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, particularly in therapeutic areas like oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine-containing group enhances efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty chemicals, including organic electronic materials and advanced polymers.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2,3-Dihydro-2-[4-(Trifluoromethyl)Phenyl]-4(1H)-Quinolinone
CAS No.	946049-56-5
Molecular Formula	C₁₆H₁₀F₃NO
Molecular Weight	289.25 g/mol
Synonyms	2-[4-(Trifluoromethyl)phenyl]-1,2,3,4-tetrahydro-4-quinolinone; 2-(4-Trifluoromethylphenyl)-2,3-dihydro-4(1H)-quinolinone; 4(1H)-Quinolinone, 2,3-dihydro-2-[4-(trifluoromethyl)phenyl]-; 2,3-Dihydro-2-(4-trifluoromethylphenyl)-4(1H)-quinolinone; 2-(4-Trifluoromethylphenyl)-1,2,3,4-tetrahydroquinolin-4-one
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-2-[4-(Trifluoromethyl)Phenyl]-4(1H)-Quinolinone is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.