Description

1,2,3,4-Tetrahydro-5-Iodo-1,8-Naphthyridine CAS NO 945600-06-6 is a halogenated naphthyridine derivative, a high-value chemical intermediate prized for its unique fused heterocyclic structure. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile naphthyridine scaffold and iodine moiety for further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) in material science applications.
• Agrochemical Synthesis: Acts as a precursor in the development of new-generation herbicides and pesticides with enhanced efficacy.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic and Industrial R&D: Utilized in exploratory synthetic chemistry for the development of new heterocyclic compounds with potential biological activity.

Basic Information

Product Name	1,2,3,4-Tetrahydro-5-Iodo-1,8-Naphthyridine
CAS No.	945600-06-6
Molecular Formula	C8H9IN2
Molecular Weight	260.08 g/mol
Synonyms	5-Iodo-1,2,3,4-tetrahydro-1,8-naphthyridine; 5-Iodo-1,8-naphthyridine, 1,2,3,4-tetrahydro-; Tetrahydro-5-iodo-1,8-naphthyridine; 1,2,3,4-Tetrahydro-5-iodo-1,8-naphthyridin; 945600-06-6; SCHEMBL21805527; DTXSID60664669
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-5-Iodo-1,8-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.