Description

Bis[(Dicyclohexyl)(4-Dimethylaminophenyl)Phosphine] Palladium(II) Chloride, (A-Caphos)2PdCl2 is a highly specialized, air-stable palladium catalyst complex designed for demanding cross-coupling reactions. Its core value lies in the unique electronic and steric properties of the A-Caphos ligand, which provide exceptional activity and selectivity, particularly for challenging substrates. This catalyst is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable performance in synthesizing complex organic molecules. Consistent quality and reliable supply are paramount for ensuring reproducible results in critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi cross-coupling reactions in API development.
• Agrochemical Research: Enables the construction of complex heterocyclic and biaryl structures found in modern crop protection agents.
• Materials Science: Used in the synthesis of conjugated polymers, organic semiconductors, and liquid crystals for electronic applications.
• Academic & Industrial R&D: A preferred catalyst for methodological development and exploring new C-C and C-N bond-forming reactions.
• Scale-up Process Chemistry: Its stability and defined activity profile support the transition from laboratory discovery to pilot and commercial-scale manufacturing.
• Fine Chemical Production: Facilitates the efficient and selective synthesis of high-value, structurally complex specialty chemicals.

Basic Information

Product Name	Bis[(Dicyclohexyl)(4-Dimethylaminophenyl)Phosphine] Palladium(II) Chloride
CAS No.	945375-77-9
Molecular Formula	C56H84Cl2N2P2Pd
Molecular Weight	1030.48 g/mol
Synonyms	Bis(dicyclohexyl(4-(dimethylamino)phenyl)phosphine)palladium(II) dichloride; (A-Caphos)2PdCl2; A-Caphos Palladium(II) Chloride Dimer; Dichlorobis[(4-dimethylaminophenyl)dicyclohexylphosphine]palladium(II); Palladium, dichlorobis[(4-(dimethylamino)phenyl)dicyclohexylphosphine]-; Pd(A-Caphos)2Cl2
EINECS	Contact for details

Quality Control

Every batch of (A-Caphos)2PdCl2 is manufactured and tested under strict quality management systems to ensure the high purity and consistent catalytic performance required for sensitive synthetic applications. Our quality control protocol includes comprehensive analytical characterization to verify identity, purity, and the absence of deleterious impurities. A Certificate of Analysis (COA) detailing specific batch results is provided with each shipment, offering full traceability and assurance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air or light may degrade performance.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Pd Content (ICP-OES)	10.0 - 10.5 %
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.