Description

Methanesulfonato(1,1-Bis(Diphenylphosphino)Ferrocene)(2'-Methylamino-1,1'-Biphenyl-2-Yl)Palladium(II) is a highly specialized, air-stable palladium catalyst featuring a ferrocenyl diphosphine ligand, designed for superior performance in demanding cross-coupling reactions. This compound matters because it offers exceptional catalytic activity and selectivity, enabling efficient synthesis of complex molecules in high-value chemical production. It is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and fine chemicals. The CAS number for this product is 1621274-17-6.

Application

This advanced palladium catalyst is engineered for high-performance applications in synthetic chemistry, particularly where challenging substrates are involved.

• Pharmaceutical Intermediate Synthesis: Key catalyst for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions to construct carbon-nitrogen and carbon-carbon bonds in drug candidates.
• Agrochemical Production: Used in the synthesis of complex, nitrogen-containing heterocycles found in modern pesticides and herbicides.
• Material Science R&D: Facilitates the polymerization and functionalization of organic semiconductors and conductive polymers.
• Academic & Industrial Research: A valuable tool for methodology development and exploring new reaction pathways in organometallic chemistry.
• Scale-up Process Chemistry: Suitable for optimizing and transferring laboratory-scale reactions to pilot plant and manufacturing scales due to its robustness.

Basic Information

Item	Details
Product Name	Methanesulfonato(1,1-Bis(Diphenylphosphino)Ferrocene)(2'-Methylamino-1,1'-Biphenyl-2-Yl)Palladium(II)
CAS No.	1621274-17-6
Molecular Formula	C48H43FeNO3P2PdS
Molecular Weight	938.10 g/mol
Synonyms	Palladium(II) methanesulfonate Josiphos complex; [Pd(MeCN)(JosiPhos)](OTf) analog; (2'-Methylamino[1,1'-biphenyl]-2-yl)(η5-cyclopentadienyl){1,1'-[1,1'-bis(diphenylphosphino)ferrocene]}palladium(II) methanesulfonate; Pd-JosiPhos-amine precatalyst; Air-stable Pd precatalyst; Buchwald-Hartwig precatalyst; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of Methanesulfonato(1,1-Bis(Diphenylphosphino)Ferrocene)(2'-Methylamino-1,1'-Biphenyl-2-Yl)Palladium(II) adheres to stringent quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to verify identity, purity, and the absence of deleterious impurities like free palladium black. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient temperature should be avoided.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	~11.3% (Theoretical)
Solubility	Soluble in common organic solvents (DCM, THF, Acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.