Description

tert-Butyl 4-Amino-3,4-dihydroquinoline-1(2H)-carboxylate is a high-purity, protected amine derivative of the dihydroquinoline scaffold, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive amino group that is shielded by a Boc (tert-butoxycarbonyl) protecting group, enabling precise control in multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the quinoline core for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles and natural product analogs.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers and advanced organic materials.

Basic Information

Product Name	tert-Butyl 4-Amino-3,4-dihydroquinoline-1(2H)-carboxylate
CAS No.	944906-95-0
Molecular Formula	C14H18N2O2
Molecular Weight	246.31 g/mol
Synonyms	1-Boc-4-amino-1,2,3,4-tetrahydroquinoline; 4-Amino-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; tert-Butyl 4-amino-1,2,3,4-tetrahydroquinoline-1-carboxylate; 1,2,3,4-Tetrahydro-4-aminoquinoline-1-carboxylic acid tert-butyl ester; 4-Amino-1-Boc-1,2,3,4-tetrahydroquinoline; Boc-4-ATQ; 1-N-Boc-4-amino-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-3,4-dihydroquinoline-1(2H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.