Description

5-(Trifluoromethyl)-4H-1,2,4-Triazole-3-Carbaldehyde is a high-value trifluoromethylated heterocyclic building block. This compound is essential for introducing the trifluoromethyl-triazole pharmacophore, which can significantly alter the physicochemical and biological properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the development of new drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the CF3 group enhances metabolic stability and lipophilicity.
• Material Science Research: Serves as a precursor for functionalized ligands, metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes due to its reactive aldehyde group.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-(Trifluoromethyl)-4H-1,2,4-Triazole-3-Carbaldehyde
CAS No.	944906-25-6
Molecular Formula	C4H2F3N3O
Molecular Weight	165.08 g/mol
Synonyms	4H-1,2,4-Triazole-3-carboxaldehyde, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-1,2,4-triazole-3-carbaldehyde; 3-Formyl-5-(trifluoromethyl)-1,2,4-triazole; 5-Trifluoromethyl-4H-1,2,4-triazole-3-carboxaldehyde; 5-Trifluoromethyl-1,2,4-triazole-3-carbaldehyde; 944906-25-6; 5-(Trifluoromethyl)-1H-1,2,4-triazole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-4H-1,2,4-Triazole-3-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.