Description

5-Fluorospiro[1,2-Dihydroindole-3,4'-Piperidine] is a high-value, spirocyclic organic compound featuring a unique fused indole-piperidine structure. This compound serves as a critical pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research, enabling the development of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Scaffold: Used in hit-to-lead and lead optimization programs to explore structure-activity relationships (SAR) due to its three-dimensional, spirocyclic framework.
• Chemical Biology Probe: Employed in the development of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Serves as a precursor in the discovery of new active ingredients for crop protection.
• Academic & Contract Research: Utilized in university and CRO settings for synthetic methodology development and novel heterocycle synthesis.

Basic Information

Product Name	5-Fluorospiro[1,2-Dihydroindole-3,4'-Piperidine]
CAS No.	944905-36-6
Molecular Formula	C13H15FN2
Molecular Weight	218.27 g/mol
Synonyms	5-Fluoro-1,2-dihydrospiro[indole-3,4'-piperidine]; 5-Fluoro-2,3-dihydro-1H-spiro[indole-3,4'-piperidine]; 5-Fluoro-1H-spiro[indole-3,4'-piperidine]; 5-Fluoro-2,3-dihydrospiro[indole-3,4'-piperidine]; Spiro[1,2-dihydroindole-3,4'-piperidine], 5-fluoro-; 944905-36-6; 5-Fluorospiroindolepiperidine
EINECS	Contact for details

Quality Control

We supply 5-Fluorospiro[1,2-Dihydroindole-3,4'-Piperidine] in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.