Description

2-(2,2,2-Trifluoroethoxy)Pyrimidine-5-Carbaldehyde is a high-value pyrimidine derivative and a versatile trifluoroethoxy-functionalized building block for advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts desirable metabolic stability and lipophilicity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides with improved efficacy.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and target engagement.
• Fluorinated Compound Library: An essential component for generating diverse fluorinated compound libraries for high-throughput screening.
• Advanced Material Research: Investigated for the synthesis of fluorinated polymers and electronic materials with specific properties.

Basic Information

Product Name	2-(2,2,2-Trifluoroethoxy)Pyrimidine-5-Carbaldehyde
CAS No.	944904-99-8
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	5-Formyl-2-(2,2,2-trifluoroethoxy)pyrimidine; Pyrimidine-5-carboxaldehyde, 2-(2,2,2-trifluoroethoxy)-; 2-(Trifluoroethoxy)pyrimidine-5-carbaldehyde; 2-(2,2,2-Trifluoroethoxy)-5-pyrimidinecarboxaldehyde; 5-Pyrimidinecarboxaldehyde, 2-(2,2,2-trifluoroethoxy)-; 944904-99-8; 2-(2,2,2-Trifluoroethoxy)pyrimidine-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-(2,2,2-Trifluoroethoxy)Pyrimidine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.