Description

3-Iodo-1H-Indazole-6-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates both an iodine substituent and an aldehyde functional group on the indazole scaffold, enabling diverse and complex chemical transformations. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides by serving as a core scaffold for novel active ingredients.
• Material Science: Acts as a building block for creating specialized organic ligands, polymers, and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Medicinal Chemistry SAR Studies: The aldehyde group allows for facile derivatization (e.g., reductive amination, condensation) to rapidly explore structure-activity relationships.

Basic Information

Item	Details
Product Name	3-Iodo-1H-Indazole-6-Carbaldehyde
CAS No.	944904-42-1
Molecular Formula	C8H5IN2O
Molecular Weight	288.04 g/mol
Synonyms	6-Formyl-3-iodo-1H-indazole; 3-Iodo-1H-indazole-6-carboxaldehyde; 1H-Indazole-6-carboxaldehyde, 3-iodo-; 3-Iodo-6-indazolecarboxaldehyde; 3-Iodoindazole-6-carbaldehyde; 944904-42-1; 3-Iodo-1H-indazol-6-yl-methanal
EINECS	Contact for details

Quality Control

Our 3-Iodo-1H-Indazole-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.