Description

2-Chloro-6-(Trifluoromethyl)Nicotinaldehyde is a high-value, multi-functional pyridine derivative and a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a reactive aldehyde group and a chloro-trifluoromethyl substituted pyridine ring, makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers and non-linear optical (NLO) materials.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Nicotinaldehyde
CAS No.	944900-06-5
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	2-Chloro-6-(trifluoromethyl)pyridine-3-carbaldehyde; 3-Formyl-2-chloro-6-(trifluoromethyl)pyridine; 2-Chloro-6-trifluoromethylnicotinaldehyde; 2-Chloro-6-(trifluoromethyl)-3-pyridinecarboxaldehyde; 944900-06-5; Nicotinaldehyde, 2-chloro-6-(trifluoromethyl)-; 2-Chloro-6-trifluoromethyl-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(Trifluoromethyl)Nicotinaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.