Description

1-(2-Fluorobenzyl)-1H-Indole-5-Carbaldehyde is a high-purity fluorinated indole derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a reactive aldehyde group with a fluorinated benzyl moiety, enabling precise structural modifications for targeted molecule development. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in oncology and CNS (Central Nervous System) research.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways due to its modifiable aldehyde handle.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	1-(2-Fluorobenzyl)-1H-Indole-5-Carbaldehyde
CAS No.	944893-62-3
Molecular Formula	C16H12FNO
Molecular Weight	253.27 g/mol
Synonyms	5-Formyl-1-[(2-fluorophenyl)methyl]-1H-indole; 1H-Indole-5-carboxaldehyde, 1-[(2-fluorophenyl)methyl]-; 1-(2-Fluorobenzyl)indole-5-carboxaldehyde; 1-[(2-Fluorophenyl)methyl]-1H-indole-5-carbaldehyde; 2-Fluorobenzyl Indole-5-Carboxaldehyde; 944893-62-3; FC-IC Aldehyde
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluorobenzyl)-1H-Indole-5-Carbaldehyde adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.