Description

1-(2-Fluorobenzyl)-1H-Indole-6-Carbaldehyde is a high-purity fluorinated indole derivative, a crucial building block in advanced organic synthesis. Its molecular architecture, featuring both an indole core and a fluorinated benzyl group, makes it a versatile intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical developers engaged in medicinal chemistry, particularly for the synthesis of novel drug candidates and bioactive probes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Agrochemical Synthesis: Serves as an intermediate in the development of advanced pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science Precursor: Potential use in the synthesis of specialized organic electronic materials or fluorescent dyes due to the conjugated indole-aldehyde system.
• Biochemical Tool Development: Employed in the creation of enzyme inhibitors or receptor ligands for biochemical and pharmacological assays.

Basic Information

Product Name	1-(2-Fluorobenzyl)-1H-Indole-6-Carbaldehyde
CAS No.	944893-43-0
Molecular Formula	C₁₆H₁₂FNO
Molecular Weight	253.27 g/mol
Synonyms	6-Formyl-1-[(2-fluorophenyl)methyl]-1H-indole; 1-[(2-Fluorophenyl)methyl]-1H-indole-6-carboxaldehyde; 1-(2-Fluorobenzyl)indole-6-carbaldehyde; 1H-Indole-6-carbaldehyde, 1-[(2-fluorophenyl)methyl]-; 944893-43-0; 1-(2-Fluorobenzyl)-6-formylindole; 1-(2-Fluorobenzyl)-1H-indole-6-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Fluorobenzyl)-1H-Indole-6-Carbaldehyde is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.