Description

Ethanone, 1-(1,2-Dihydrospiro[Cyclopropane-1,3-[3H]Indol]-1-Yl)- is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indole scaffold. This compound is of significant value for medicinal chemistry research and development, offering a versatile building block for constructing complex molecular architectures. It is primarily sought after by R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its spirocyclic indole core.
• Organic Synthesis: Serves as a versatile precursor for the construction of complex heterocyclic compounds and natural product analogs.
• Biochemical Research: Potential use as a probe or ligand in biochemical assays and for studying protein-ligand interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Ethanone, 1-(1,2-Dihydrospiro[Cyclopropane-1,3-[3H]Indol]-1-Yl)-
CAS No.	944828-13-1
Molecular Formula	C12H13NO
Molecular Weight	187.24 g/mol
Synonyms	1-(1,2-Dihydrospiro[cyclopropane-1,3'-indol]-1'-yl)ethanone; 1-(1,2-Dihydrospiro[cyclopropane-1,3-[3H]indol]-1-yl)ethan-1-one; Spiro[cyclopropane-1,3'-indole]-1'-yl methyl ketone; 1'-Acetyl-1,2-dihydrospiro[cyclopropane-1,3'-indole]; 1,2-Dihydrospiro[cyclopropane-1,3'-indol]-1'-yl methyl ketone; 1-(1,2-Dihydrospiro[cyclopropane-1,3'-indol]-1'-yl)ethanone; CAS 944828-13-1
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(1,2-Dihydrospiro[Cyclopropane-1,3-[3H]Indol]-1-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality standards are designed to meet the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.