Description

5-Bromo-4-Fluoro-2-Nitrophenol is a halogenated nitrophenol derivative, a versatile and high-value synthetic building block in advanced organic chemistry. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials who require reliable access to high-purity, structurally defined intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogen and nitro functional groups for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of probes, tags, and inhibitors for studying biological systems.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex azo dyes and pigments with specific color and stability properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create biaryl structures.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Nitrophenol
CAS No.	944805-22-5
Molecular Formula	C6H3BrFNO3
Molecular Weight	235.99 g/mol
Synonyms	2-Nitro-5-bromo-4-fluorophenol; 4-Fluoro-5-bromo-2-nitrophenol; Phenol, 5-bromo-4-fluoro-2-nitro-; 5-Bromo-4-fluoro-2-nitro-1-hydroxybenzene; 2-Nitrophenol, 5-bromo-4-fluoro-; 944805-22-5 (CAS); 5-Br-4-F-2-NO2-PhOH
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Fluoro-2-Nitrophenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.