Description

3-Nitrobenzyl Bromide is a versatile and reactive aromatic building block, primarily valued for its bromomethyl functional group which serves as a key handle for further chemical transformations. This compound is essential for researchers and manufacturers requiring precise, high-purity intermediates in complex synthetic pathways. It is particularly critical for the development of active pharmaceutical ingredients (APIs), advanced agrochemicals, and specialized organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring benzyl-protected amine or ether functionalities.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the nitro and bromomethyl groups enable the construction of complex bioactive molecules.
• Organic Synthesis & Research: Serves as a fundamental building block for alkylation reactions, the preparation of protected intermediates, and in cross-coupling methodologies in academic and industrial R&D laboratories.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized phosphine ligands, N-heterocyclic carbene (NHC) precursors, and other organocatalysts used in asymmetric synthesis.
• Material Science: Acts as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye & Pigment Manufacturing: Utilized as an intermediate in the synthesis of complex azo dyes and other nitro-aromatic based colorants.

Basic Information

Product Name	3-Nitrobenzyl Bromide
CAS No.	3958-57-4
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	α-Bromo-3-nitrotoluene; m-Nitrobenzyl Bromide; 1-(Bromomethyl)-3-nitrobenzene; 3-Nitrobenzylbromide; (3-Nitrophenyl)methyl bromide; NSC 404087; Benzene, 1-(bromomethyl)-3-nitro-
EINECS	223-553-2

Quality Control

Our 3-Nitrobenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	72 - 76 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.