Description

(2-Chloro-3-Fluorophenyl)Methanamine Hydrochloride is a high-purity, synthetically valuable aromatic amine hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile building block for advanced chemical synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the chloro-fluoro-phenyl moiety.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other advanced synthetic methodologies.
• Material Science Research: Intermediate for creating novel polymers, liquid crystals, or organic electronic materials with specific functional properties.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes.
• Academic and R&D Laboratories: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.

Basic Information

Product Name	(2-Chloro-3-Fluorophenyl)Methanamine Hydrochloride
CAS No.	944736-39-4
Molecular Formula	C7H8Cl2FN
Molecular Weight	204.05 g/mol
Synonyms	1-(2-Chloro-3-fluorophenyl)methanamine hydrochloride; (2-Chloro-3-fluorobenzyl)amine hydrochloride; 2-Chloro-3-fluorobenzylamine hydrochloride; α-Amino-2-chloro-3-fluorotoluene hydrochloride; Benzenemethanamine, 2-chloro-3-fluoro-, hydrochloride; 2-Chloro-3-fluoro-α-toluidine hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Chloro-3-Fluorophenyl)Methanamine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.