Description

Ethyl 4-Chloro-1,8-naphthyridine-3-carboxylate is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex heterocyclic scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or oncology, leveraging the bioactive naphthyridine core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the chlorinated naphthyridine structure can impart specific biological activity.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Synthesis: Versatile building block for further functionalization via cross-coupling reactions, nucleophilic substitutions, or hydrolysis to access carboxylic acid derivatives.
• Academic & Contract Research: Essential reagent for methodological studies and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Ethyl 4-Chloro-1,8-naphthyridine-3-carboxylate
CAS No.	944709-62-0
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.66 g/mol
Synonyms	Ethyl 4-chloro-1,8-naphthyridine-3-carboxylate; 4-Chloro-1,8-naphthyridine-3-carboxylic acid ethyl ester; 3-Carbethoxy-4-chloro-1,8-naphthyridine; 1,8-Naphthyridine-3-carboxylic acid, 4-chloro-, ethyl ester; Ethyl 4-chloro-1,8-naphthyridine-3-carboxylate (CAS 944709-62-0); 4-Chloro-3-(ethoxycarbonyl)-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-1,8-naphthyridine-3-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.