Description

Chloro{(S)-(+)-5,5'-Bis[Di(3,5-Di-T-Butyl-4-Methoxyphenyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}(p-Cymene)Ruthenium(II) Chloride[Rucl(p-Cymene) ((S)-Dtbm-Segphos)]Cl is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters for its exceptional performance as a precise and efficient catalyst in enantioselective hydrogenation and other critical synthetic transformations. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require high enantiomeric purity in their advanced intermediates and active ingredients.

Application

• Asymmetric Hydrogenation Catalyst: Key for the enantioselective synthesis of chiral amines, amino acids, and alcohols, which are vital building blocks for active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Enables the production of high-value, single-enantiomer compounds for drug development, reducing the need for costly chiral separations.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and pesticides where biological activity is often enantiomer-specific.
• Fine Chemical Production: Facilitates the creation of complex, optically pure molecules for flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: Serves as a critical tool for methodology development and exploring new catalytic pathways in organic synthesis.
• Process Chemistry Optimization: Employed in scaling up enantioselective reactions from laboratory to pilot plant and commercial production scales.

Basic Information

Item	Details
Product Name	Chloro{(S)-(+)-5,5'-Bis[Di(3,5-Di-T-Butyl-4-Methoxyphenyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}(p-Cymene)Ruthenium(II) Chloride[Rucl(p-Cymene) ((S)-Dtbm-Segphos)]Cl
CAS No.	944451-33-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RuCl(p-cymene)[(S)-DTBM-SEGPHOS)]Cl; [(S)-DTBM-SEGPHOS]RuCl(p-cymene) chloride; (S)-DTBM-SEGPHOS Ru(II) p-cymene chloride complex; Ruthenium(II) chloro(p-cymene)[(S)-5,5'-bis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole]; Asymmetric hydrogenation catalyst Ru-DTBM-SEGPHOS; Ru/(S)-DTBM-SEGPHOS catalyst; CAS 944451-33-6
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and catalytic activity, supporting reproducible and reliable performance in your critical syntheses. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is moisture-sensitive (hygroscopic) and easily oxidized; therefore, containers must be sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Solubility	Soluble in common organic solvents (e.g., DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.