Description

Chloro{(R)-(-)-5,5'-Bis[Di(3,5-Di-T-Butyl-4-Methoxyphenyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}(p-Cymene)Ruthenium(Ii)Chloride[Rucl(p-Cymene) ((R)-Dtbm-Segphos)]Cl is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters for its exceptional enantioselectivity and catalytic efficiency in key synthetic transformations, enabling the production of high-value, optically pure intermediates. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic routes and scaling up production of chiral molecules.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of functionalized olefins, ketones, and imines, critical for producing chiral alcohols and amines in pharmaceutical synthesis.
• Pharmaceutical Intermediate Synthesis: Enables the efficient and selective construction of complex, single-enantiomer active pharmaceutical ingredients (APIs) and key building blocks.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is essential for biological activity.
• Fine Chemical Production: Facilitates the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial R&D: Serves as a vital tool in methodological development for new catalytic asymmetric reactions and process optimization studies.
• Process Chemistry & Scale-up: Employed in pilot plants and commercial manufacturing where robust and selective catalysts are required for cost-effective production.

Basic Information

Product Name	Chloro{(R)-(-)-5,5'-Bis[Di(3,5-Di-T-Butyl-4-Methoxyphenyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}(p-Cymene)Ruthenium(Ii)Chloride[Rucl(p-Cymene) ((R)-Dtbm-Segphos)]Cl
CAS No.	944451-32-5
Molecular Formula	C96H118Cl2O8P2Ru
Molecular Weight	1590.78 g/mol
Synonyms	RuCl(p-cymene)[(R)-DTBM-SEGPHOS)]Cl; [(R)-DTBM-SEGPHOS]RuCl(p-cymene) chloride; (R)-DTBM-SEGPHOS Ru(II) p-cymene chloride complex; Ruthenium(II) (R)-DTBM-SEGPHOS p-cymene chloride; (R)-5,5'-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole chlororuthenium p-cymene complex; RuCl[(R)-DTBM-SEGPHOS](p-cymene)Cl; Asymmetric hydrogenation catalyst Ru-DTBM-SEGPHOS; CAS 944451-32-5
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is produced and tested under strict quality management protocols to ensure consistent high performance and enantioselectivity. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral integrity, and catalytic activity. Our quality systems support development under cGMP guidelines where required, ensuring reliability for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and decomposition. Allow the container to reach room temperature in a dry environment before opening to minimize moisture exposure.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Ruthenium Content	Contact for details
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.