Description

Chloro[(S)-(-)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl](p-Cymene)Ruthenium(II) Chloride [RuCl(p-Cymene)((S)-H8-Binap)]Cl is a high-value, chiral ruthenium complex designed for advanced asymmetric catalysis. This compound matters because it serves as a highly efficient and selective catalyst for hydrogenation and other key transformations in fine chemical synthesis, enabling the production of enantiomerically pure intermediates. It is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control in their synthetic routes.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of functionalized olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Chiral Ligand Precursor: Serves as a source of the (S)-H8-BINAP ligand for the preparation of other metal complexes.
• Pharmaceutical Intermediate Production: Key for synthesizing active pharmaceutical ingredients (APIs) with specific chiral centers, such as certain antibiotics and cardiovascular drugs.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Process R&D: A valuable tool for developing new catalytic methodologies and optimizing reaction conditions in laboratory-scale research.
• Fine Chemical Manufacturing: Enables the cost-effective and scalable production of complex, high-value chiral molecules for various industrial applications.

Basic Information

Product Name	Chloro[(S)-(-)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl](p-Cymene)Ruthenium(II) Chloride
CAS No.	944451-27-8
Molecular Formula	C58H56Cl2P2Ru
Molecular Weight	974.93 g/mol
Synonyms	RuCl(p-cymene)[(S)-H8-BINAP]Cl; Ruthenium(II) Chloride (p-cymene)((S)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene-2,2'-diyl)bis(diphenylphosphine) Chloride; (S)-H8-BINAP Ru(p-cymene)Cl Cl; (S)-(-)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl (p-cymene)ruthenium(II) chloride; (S)-H8-BINAP Ru(II) (p-cymene) chloride complex; [RuCl((S)-H8-binap)(p-cymene)]Cl
EINECS	Contact for details

Quality Control

Our Chloro[(S)-(-)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl](p-Cymene)Ruthenium(II) Chloride is manufactured under controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous quality testing, including spectroscopic analysis and purity assays, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This material is easily oxidized and light-sensitive; prolonged exposure to air or light may degrade its catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation ([α]D20)	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.