Description

Chloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}(p-Cymene)Ruthenium(II) Chloride [RuCl(p-Cymene)((S)-Xylbinap)]Cl is a high-value, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a highly efficient and enantioselective catalyst for critical hydrogenation and transfer hydrogenation reactions in fine chemical synthesis. Pharmaceutical, agrochemical, and advanced material researchers need it to produce chiral intermediates with high optical purity and excellent yield.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins in pharmaceutical intermediate synthesis.
• Transfer Hydrogenation Reactions: Utilizing hydrogen donors like isopropanol or formic acid for reduction processes under mild conditions.
• Chiral Ligand Precursor: The (S)-Xylbinap ligand framework can be utilized in other metal-catalyzed asymmetric transformations.
• Synthesis of Optically Active Compounds: Production of chiral alcohols, amines, and acids for active pharmaceutical ingredients (APIs) and agrochemicals.
• Academic and Industrial R&D: For method development and scaling up novel asymmetric synthetic routes.
• Fine Chemical Manufacturing: Enabling cost-effective and sustainable production of high-value specialty chemicals with precise stereocontrol.

Basic Information

Product Name	Chloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}(p-Cymene)Ruthenium(II) Chloride [RuCl(p-Cymene)((S)-Xylbinap)]Cl
CAS No.	944451-25-6
Molecular Formula	C78H72Cl2P2Ru
Molecular Weight	1248.70 g/mol
Synonyms	RuCl(p-cymene)[(S)-Xylbinap]Cl; (S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl (p-Cymene)Ruthenium(II) Chloride; (S)-Xylbinap Ru(p-cymene)Cl complex; Dichloro[(S)-(-)-2,2'-bis[di(3,5-xylyl)phosphino]-1,1'-binaphthyl](p-cymene)ruthenium(II); (S)-Xyl-BINAP Ru(II) (p-cymene) chloride; Asymmetric Ruthenium Xylbinap Catalyst; Ru-Xylbinap Catalyst; [RuCl((S)-Xylbinap)(p-cymene)]Cl
EINECS	Contact for details

Quality Control

Our Chloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}(p-Cymene)Ruthenium(II) Chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and metal content. We adhere to cGMP guidelines where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Ruthenium Content	7.8 - 8.2%
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.