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Diacetato{(R)-(+)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}Ruthenium(Ii) Ru(Oac)2[(R)-Dm-Segphos] CAS NO 944450-50-4
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CAS No.:944450-50-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Diacetato{(R)-(+)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}Ruthenium(Ii) Ru(Oac)2[(R)-Dm-Segphos] is a high-purity, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a highly efficient and selective catalyst for critical hydrogenation and reduction reactions in fine chemical synthesis. It is primarily needed by pharmaceutical R&D laboratories and advanced chemical manufacturers for producing enantiomerically pure intermediates and active pharmaceutical ingredients (APIs).
Application
- Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and olefins in pharmaceutical intermediate synthesis.
- Pharmaceutical API Manufacturing: Key for producing chiral drug molecules with high optical purity, including antibiotics, cardiovascular agents, and CNS drugs.
- Fine Chemical Synthesis: Enables the production of high-value chiral building blocks for agrochemicals, flavors, and fragrances.
- Academic & Industrial R&D: Used in process development and optimization studies for new catalytic methodologies.
- Chiral Technology Development: A critical tool for exploring new asymmetric transformations in organic chemistry.
Basic Information
| Item | Details |
|---|---|
| Product Name | Diacetato{(R)-(+)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}Ruthenium(Ii) Ru(Oac)2[(R)-Dm-Segphos] |
| CAS No. | 944450-50-4 |
| Molecular Formula | C66H66O6P2Ru |
| Molecular Weight | 1100.22 g/mol |
| Synonyms | Ru(OAc)2[(R)-DM-SEGPHOS]; (R)-DM-SEGPHOS Ru(II) Diacetate; Ruthenium(II) (R)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole Diacetate; (R)-DM-SEGPHOS Ru diacetate; Asymmetric Hydrogenation Catalyst Ru(DM-SEGPHOS)(OAc)2; Ru/(R)-DM-SEGPHOS complex; CAS 944450-50-4 |
| EINECS | Contact for details |
Quality Control
Our Diacetato{(R)-(+)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}Ruthenium(Ii) Ru(Oac)2[(R)-Dm-Segphos] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques, and a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral integrity is provided. We adhere to cGMP standards where applicable to support pharmaceutical development.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the sealed container to reach room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red-brown crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Ruthenium Content | Contact for details |
| Solubility | Soluble in common organic solvents (DCM, THF, Toluene) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






