Description

Diacetato[(R)-(+)-5,5'-Bis(Diphenylphosphino)-4,4'-Bi-1,3-Benzodioxole] Ruthenium(II) Ru(OAc)2[(R)-Segphos] is a high-performance, chiral ruthenium complex widely recognized as a premier catalyst for asymmetric hydrogenation and other enantioselective transformations. Its value lies in providing exceptional stereoselectivity and high catalytic activity, enabling the efficient synthesis of optically pure intermediates critical for advanced pharmaceuticals and fine chemicals. This catalyst is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop chiral active pharmaceutical ingredients (APIs) and other high-value enantiomerically enriched compounds.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral ketones, olefins, and imines to produce chiral alcohols, amines, and other building blocks.
• Pharmaceutical Intermediate Synthesis: Key for manufacturing chiral active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee).
• Fine Chemical Production: Used in the synthesis of complex, high-value chiral molecules for agrochemicals, flavors, and fragrances.
• Academic and Industrial R&D: A valuable tool for method development and exploring new enantioselective reaction pathways in process chemistry.
• Chiral Ligand Precursor: Serves as a source of the (R)-Segphos ligand for in-situ catalyst formation or other metal complex synthesis.

Basic Information

Product Name	Diacetato[(R)-(+)-5,5'-Bis(Diphenylphosphino)-4,4'-Bi-1,3-Benzodioxole] Ruthenium(II)
CAS No.	944450-48-0
Molecular Formula	C58H48O6P2Ru
Molecular Weight	1000.02 g/mol
Synonyms	Ru(OAc)2[(R)-Segphos]; Ruthenium(II) acetate (R)-Segphos complex; (R)-Segphos Ru diacetate; Dichloro[(R)-(-)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl]ruthenium(II) (common mis-assignment); (R)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole ruthenium(II) diacetate; Asymmetric hydrogenation catalyst Ru-(R)-Segphos; [Ru((R)-segphos)(OAc)2]; CAS 944450-48-0
EINECS	Contact for details

Quality Control

Our Diacetato[(R)-(+)-5,5'-Bis(Diphenylphosphino)-4,4'-Bi-1,3-Benzodioxole] Ruthenium(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing specific results for assay, metal content, and chiral purity are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is moisture-sensitive and easily oxidized; prolonged exposure to air, light, or ambient humidity should be avoided to maintain catalytic activity and shelf life.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Ruthenium (Ru) Content	10.0 - 10.5 %
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.