Description

Dichloro{(S)-(-)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}[(2S)-(+)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine]Ruthenium(II) is a highly sophisticated, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations, enabling the production of single-isomer pharmaceutical intermediates and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and olefins in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Production of chiral active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Synthesis: Creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Synthesis of specialty flavors, fragrances, and advanced material precursors requiring high optical purity.
• Academic & Industrial R&D: A key reagent for developing new catalytic methodologies and exploring novel reaction pathways in organic synthesis.
• Process Chemistry Optimization: Scaling up laboratory-scale chiral syntheses to commercial manufacturing processes.

Basic Information

Product Name	Dichloro{(S)-(-)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole}[(2S)-(+)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine]Ruthenium(II)
CAS No.	944450-44-6
Molecular Formula	C81H84Cl2NO6P2Ru
Molecular Weight	1380.36 g/mol
Synonyms	Ru-SYNPHOS-DM-DPEN Catalyst; Dichloro[(S)-(-)-5,5'-bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole][(2S)-(+)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium; (S)-Ru-SYNPHOS-(S)-DADPEN; Ruthenium(II) SYNPHOS-DADPEN complex; Asymmetric Hydrogenation Catalyst 944450-44-6; [RuCl2((S)-SYNPHOS)((S)-DADPEN)]; Chiral Ru-Diphosphine-Diamine Complex
EINECS	Contact for details

Quality Control

Our high-purity chiral ruthenium catalysts are manufactured under controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for chiral purity, NMR for structural confirmation, and elemental analysis. Certificates of Analysis (COA) detailing all specifications are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.