Description

7-Fluoro-8-Methyl-3,4-Dihydroquinolin-2(1H)-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused quinolinone ring system, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated quinolinone scaffold.
• Material Science Research: Serves as a precursor for developing organic electronic materials, ligands for catalysis, and fluorescent dyes.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel fluorination and cyclization reactions.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) producing custom fine chemicals for client projects.

Basic Information

Product Name	7-Fluoro-8-Methyl-3,4-Dihydroquinolin-2(1H)-One
CAS No.	944407-14-1
Molecular Formula	C₁₀H₁₀FNO
Molecular Weight	179.19 g/mol
Synonyms	7-Fluoro-8-methyl-1,2,3,4-tetrahydroquinolin-2-one; 8-Methyl-7-fluoro-3,4-dihydro-2(1H)-quinolinone; 7-Fluoro-8-methyl-3,4-dihydro-1H-quinolin-2-one; 7-Fluoro-8-methyl-1,2,3,4-tetrahydroquinolin-2-one; 2(1H)-Quinolinone, 7-fluoro-8-methyl-3,4-dihydro-; 7-Fluoro-8-methyl-3,4-dihydroquinolin-2-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-8-Methyl-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.