Description

8-Bromo-Quinoline-5-Carbaldehyde is a versatile and high-value brominated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and an aldehyde functional group, makes it an indispensable precursor for constructing complex heterocyclic frameworks and pharmaceutical intermediates. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides that leverage the quinoline scaffold for enhanced bioactivity.
• Material Science & OLED Development: Serves as a precursor for creating organic ligands and complexing agents used in catalysis and as emissive materials in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: The reactive aldehyde and bromine groups allow for sequential functionalization via cross-coupling reactions (e.g., Suzuki, Heck), condensation, and nucleophilic substitution, enabling library synthesis for high-throughput screening.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	8-Bromo-Quinoline-5-Carbaldehyde
CAS No.	943847-26-5
Molecular Formula	C10H6BrNO
Molecular Weight	236.07 g/mol
Synonyms	5-Formyl-8-bromoquinoline; 8-Bromo-5-quinolinecarboxaldehyde; 8-Bromoquinoline-5-carbaldehyde; Quinoline-5-carbaldehyde, 8-bromo-; 8-Bromo-5-formylquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-Quinoline-5-Carbaldehyde is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with your specifications. Our quality system supports cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.