Description

2-Amino-5-(Aminomethyl)Phenol Dihydrochloride is a high-purity, dihydrochloride salt derivative of an aromatic amine-phenol compound. This material is a critical pharmaceutical intermediate and building block for the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for developing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other targeted therapies due to its amine-reactive groups.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating complex heterocycles and functionalized aromatics.
• Dye and Pigment Synthesis: Intermediate in the production of specialized dyes and colorants.
• Polymer Modification: Used to introduce amine and phenolic functionality into polymer chains for advanced material science applications.
• Biochemical Probe Development: Utilized in creating molecular probes and sensors for diagnostic applications.

Basic Information

Product Name	2-Amino-5-(Aminomethyl)Phenol Dihydrochloride
CAS No.	943751-53-9
Molecular Formula	C7H11N2O•2HCl
Molecular Weight	215.09 g/mol (Free base: 138.17 g/mol)
Synonyms	5-(Aminomethyl)-2-aminophenol dihydrochloride; 2-Amino-5-(aminomethyl)phenol hydrochloride (1:2); 1-Hydroxy-2-amino-5-(aminomethyl)benzene dihydrochloride; 3-Amino-4-hydroxybenzylamine dihydrochloride; 5-(Aminomethyl)-2-hydroxyaniline dihydrochloride; 2,5-Diaminobenzyl alcohol dihydrochloride (tautomeric form); Benzenemethanol, 3-amino-4-hydroxy-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(Aminomethyl)Phenol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for use in pharmaceutical research and development. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.