Description

8-Iodo-7-Methylquinazolin-4(3H)-One is a high-purity, functionalized quinazolinone derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling targeted molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Chemical Biology Probe: Used in medicinal chemistry to study protein-ligand interactions and structure-activity relationships (SAR).
• Material Science: Intermediate for creating novel organic electronic materials or metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential reagent for university laboratories and CROs (Contract Research Organizations) exploring heterocyclic chemistry.
• Process Chemistry: Scalable intermediate for optimizing synthetic routes in pilot plant and commercial manufacturing.

Basic Information

Product Name	8-Iodo-7-Methylquinazolin-4(3H)-One
CAS No.	943602-97-9
Molecular Formula	C9H7IN2O
Molecular Weight	286.07 g/mol
Synonyms	8-Iodo-7-methyl-3,4-dihydroquinazolin-4-one; 7-Methyl-8-iodoquinazolin-4(3H)-one; 4(3H)-Quinazolinone, 8-iodo-7-methyl-; 8-Iodo-7-methyl-4-quinazolinol; 8-Iodo-7-methylquinazolin-4-ol
EINECS	Contact for details

Quality Control

Our 8-Iodo-7-Methylquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.