Description

Quinoline, 6-[Difluoro[6-(1-Methyl-1H-Pyrazol-4-Yl)-1,2,4-Triazolo[4,3-B]Pyridazin-3-Yl]Methyl]-, Hydrochloride (10:13) is a high-purity, complex heterocyclic compound designed for advanced research and development. This specialized chemical serves as a critical building block or intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily targeted toward pharmaceutical R&D teams, agrochemical innovators, and contract research organizations (CROs) focused on developing new therapeutic and crop protection agents. The compound's unique fused triazolopyridazine-quinoline structure offers significant potential for modulating biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Research: Used as a core scaffold for designing and synthesizing novel herbicides, fungicides, or insecticides with potentially new modes of action.
• Chemical Biology Probe: Serves as a specialized tool compound for studying enzyme inhibition, receptor binding, or other biochemical pathways in academic and industrial research settings.
• Material Science Research: Potential intermediate for developing advanced organic electronic materials or metal-organic frameworks (MOFs) due to its complex, nitrogen-rich aromatic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities under cGMP conditions.

Basic Information

Product Name	Quinoline, 6-[Difluoro[6-(1-Methyl-1H-Pyrazol-4-Yl)-1,2,4-Triazolo[4,3-B]Pyridazin-3-Yl]Methyl]-, Hydrochloride (10:13)
CAS No.	943541-41-1
Molecular Formula	C19H14ClF2N7 • xHCl (Complex salt, ratio 10:13)
Molecular Weight	Contact for details
Synonyms	6-[Difluoro[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline hydrochloride (10:13); 943541-41-1; Quinoline derivative with triazolopyridazine; 6-((6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl)difluoromethyl)quinoline hydrochloride salt; Triazolopyridazine-quinoline hybrid HCl salt; [6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]-difluoro-quinolin-6-yl-methane hydrochloride
EINECS	Contact for details

Quality Control

Our production of Quinoline, 6-[Difluoro[6-(1-Methyl-1H-Pyrazol-4-Yl)-1,2,4-Triazolo[4,3-B]Pyridazin-3-Yl]Methyl]-, Hydrochloride (10:13) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up work. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development under quality systems suitable for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.