Description

Difluoro-Quinolin-6-Yl-Acetic Acid Hydrazide is a high-value, multifunctional heterocyclic building block featuring a quinoline core with fluorine and hydrazide functional groups. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical agents, enabling the introduction of key pharmacophores. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, where the fluorine atoms and heterocyclic structure enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The quinoline scaffold makes it suitable for research into fluorescent dyes and molecular probes for bio-imaging and diagnostics.
• Material Science: Employed in the research and development of advanced organic electronic materials and specialty polymers.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Difluoro-Quinolin-6-Yl-Acetic Acid Hydrazide
CAS No.	943541-39-7
Molecular Formula	C₁₃H₁₁F₂N₃O₂
Molecular Weight	279.24 g/mol
Synonyms	2-(6,8-Difluoro-4-quinolyl)acetohydrazide; 2-(6,8-Difluoroquinolin-4-yl)acetohydrazide; 6,8-Difluoro-4-quinolineacetic acid hydrazide; (6,8-Difluoroquinolin-4-yl)acetic acid hydrazide; Difluoroquinolinylacetic Acid Hydrazide; DFQAH; 943541-39-7
EINECS	Contact for details

Quality Control

Our Difluoro-Quinolin-6-Yl-Acetic Acid Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) when appropriate for long-term storage. Keep away from incompatible materials such as strong alkalis and fluorides.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.