Description

3-Piperidinamine, Dihydrochloride, (3R)- is a high-purity chiral amine salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined piperidine scaffold, essential for modulating the biological activity and pharmacokinetic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and process development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of central nervous system (CNS) active drugs, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in creating novel active ingredients for crop protection products, leveraging its amine functionality for structural diversity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, activity-based probes (ABPs), and fragment-based drug discovery libraries.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring a defined (R)-configured piperidine amine core.

Basic Information

Product Name	3-Piperidinamine, Dihydrochloride, (3R)-
CAS No.	943528-10-7
Molecular Formula	C5H14Cl2N2
Molecular Weight	173.08 g/mol
Synonyms	(3R)-3-Aminopiperidine Dihydrochloride; (R)-3-Aminopiperidine Dihydrochloride; (R)-3-Piperidinamine Dihydrochloride; (R)-Piperidin-3-amine Dihydrochloride; (3R)-Piperidin-3-amine Dihydrochloride; (R)-3-AP Dihydrochloride; (R)-3-Piperidinylamine Dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Piperidinamine, Dihydrochloride, (3R)- is manufactured under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.