Description

Ethyl p-Nitrobenzyl Carbonate is a specialized organic compound featuring a carbonate ester linkage to a p-nitrobenzyl protecting group. This chemical is of significant value in synthetic organic chemistry, particularly for the protection of alcohols and amines in multi-step synthesis, where its selective removal under mild conditions is a key advantage. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the production of complex molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block and protecting group reagent in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used for the temporary protection of hydroxyl and amino functionalities during solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Employed in the research and development of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Acts as a versatile intermediate in the manufacture of dyes, pigments, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis within university laboratories and corporate R&D centers.
• Protecting Group Chemistry: Specifically utilized for its ability to be cleaved under selective conditions (e.g., hydrogenolysis, photolysis) without affecting other sensitive functional groups.

Basic Information

Product Name	Ethyl p-Nitrobenzyl Carbonate
CAS No.	943409-69-6
Molecular Formula	C10H11NO5
Molecular Weight	225.20 g/mol
Synonyms	Ethyl 4-Nitrobenzyl Carbonate; p-Nitrobenzyl Ethyl Carbonate; 4-Nitrobenzyl Ethyl Carbonate; Carbonochloridic Acid, (4-Nitrophenyl)methyl Ester, Ethyl Ester; Ethyl (4-Nitrobenzyl) Carbonate; (4-Nitrobenzyl) Ethyl Carbonate; Ethyl Carbonate of p-Nitrobenzyl Alcohol
EINECS	Contact for details

Quality Control

Our Ethyl p-Nitrobenzyl Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.