Description

3-Cyclopropylpiperidine Hydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its unique bicyclic amine structure, which is integral to the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and scaffold hopping strategies to explore new chemical space and improve drug-like properties.
• Process Chemistry & Scale-up: Serves as a critical starting material or intermediate in the development of robust, scalable synthetic routes for API manufacturing under GMP conditions.
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides, leveraging its constrained cyclopropyl-piperidine motif.
• Ligand & Catalyst Development: Utilized as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Cyclopropylpiperidine Hydrochloride
CAS No.	942511-56-0
Molecular Formula	C8H16ClN
Molecular Weight	161.67 g/mol
Synonyms	3-Cyclopropylpiperidine HCl; Piperidine, 3-cyclopropyl-, hydrochloride; 3-Cyclopropylpiperidinium chloride; 1-(Cyclopropyl)piperidin-3-amine hydrochloride; 3-Cyclopropylpiperidin-3-amine hydrochloride (tautomer); 942511-56-0; UNII-6K8F8PZ4Q5
EINECS	Contact for details

Quality Control

Our 3-Cyclopropylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and residual solvents. We support development and commercial projects requiring material suitable for use under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.