Description

2-Methylsulfonyl-5-(Pyrrolidin-1-Yl)Aniline is a high-purity, functionalized aniline derivative featuring a methylsulfonyl electron-withdrawing group and a pyrrolidine electron-donating substituent. This unique molecular architecture makes it a valuable and versatile chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a precursor for developing new herbicides, fungicides, and insecticides, leveraging its structural motifs for bioactivity.
• Organic Synthesis & Research: Used in academic and industrial laboratories for methodological studies, including cross-coupling reactions, amide formation, and heterocyclic chemistry.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers, dyes, or photoactive materials due to its aniline core and functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	2-Methylsulfonyl-5-(Pyrrolidin-1-Yl)Aniline
CAS No.	942474-54-6
Molecular Formula	C11H16N2O2S
Molecular Weight	240.32 g/mol
Synonyms	5-(Pyrrolidin-1-yl)-2-(methylsulfonyl)aniline; 2-(Methylsulfonyl)-5-(pyrrolidin-1-yl)aniline; Benzenamine, 5-(1-pyrrolidinyl)-2-(methylsulfonyl)-; 942474-54-6; 2-Methanesulfonyl-5-pyrrolidin-1-yl-aniline; 5-Pyrrolidin-1-yl-2-methylsulfonyl-phenylamine
EINECS	Contact for details

Quality Control

Our 2-Methylsulfonyl-5-(Pyrrolidin-1-Yl)Aniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.