Description

Ethynyl p-Tolyl Sulfone is a specialized organic sulfur compound featuring an ethynyl group attached to a tolyl sulfone moiety. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of novel drug candidates, especially those requiring sulfone or acetylene functional groups.
• Agrochemical Synthesis: Used in creating advanced pesticides, herbicides, and fungicides where the sulfone moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and high-performance resins.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Sonogashira) and other catalytic processes to introduce the ethynyl-tolylsulfone unit.
• Ligand and Catalyst Development: Potential precursor for creating novel ligands used in homogeneous catalysis.
• Academic and Industrial R&D: A critical reagent for methodological studies and exploring new chemical spaces in discovery chemistry.

Basic Information

Item	Detail
Product Name	Ethynyl p-Tolyl Sulfone
CAS No.	13894-21-8
Molecular Formula	C9H8O2S
Molecular Weight	180.22 g/mol
Synonyms	1-Ethynyl-4-methylsulfonylbenzene; (4-Methylphenyl)ethynyl sulfone; p-Tolyl ethynyl sulfone; 4-Methylphenyl ethynyl sulfone; 4-(Ethynylsulfonyl)toluene; 1-Methyl-4-(ethynylsulfonyl)benzene; Ethynyl tolyl sulfone
EINECS	Contact for details

Quality Control

Our Ethynyl p-Tolyl Sulfone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance as a synthesis intermediate. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.